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Glycosaminoglycans in human retinoblastoma cells: Heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions

BACKGROUND: Pigment epithelium-derived factor (PEDF) has binding affinity for cell-surface receptors in retinoblastoma cells and for glycosaminoglycans. We investigated the effects of glycosaminoglycans on PEDF-receptor interactions. RESULTS: (125)I-PEDF formed complexes with protease-resistant comp...

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Detalles Bibliográficos
Autores principales: Alberdi, Elena M, Weldon, John E, Becerra, S Patricia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151665/
https://www.ncbi.nlm.nih.gov/pubmed/12625842
http://dx.doi.org/10.1186/1471-2091-4-1