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Human CD81 directly enhances T(h)1 and T(h)2 cell activation, but preferentially induces proliferation of T(h)2 cells upon long-term stimulation

BACKGROUND: CD81, a cell-surface protein of the tetraspanin superfamily, has been shown to costimulate T cell activation in murine T cells, and is involved in development of Th2 immune responses in mice. RESULTS: Here it is shown that stimulation of CD81 on human T cells can enhance T cell activatio...

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Detalles Bibliográficos
Autor principal: Maecker, Holden T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151668/
https://www.ncbi.nlm.nih.gov/pubmed/12597781
http://dx.doi.org/10.1186/1471-2172-4-1