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Dioxin activates HIV-1 gene expression by an oxidative stress pathway requiring a functional cytochrome P450 CYP1A1 enzyme.

We have studied the effect of several environmental chemicals on the transient expression of a chloramphenicol acetyltransferase (cat) reporter gene linked to the promoter sequences in the long terminal repeat (LTR) of the human immunodeficiency virus type 1 (HIV-1). Aflatoxin B1, 2,3,7,8-tetrachlor...

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Detalles Bibliográficos
Autores principales: Yao, Y, Hoffer, A, Chang, C Y, Puga, A
Formato: Texto
Lenguaje:English
Publicado: 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519101/
https://www.ncbi.nlm.nih.gov/pubmed/7607137