DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis.

DNA lesions that escape repair have a certain probability of giving rise to mutations when the cell divides. Endogenous DNA damage is high: 10(6) oxidative lesions are present per rat cell. An exogenous mutagen produces an increment in lesions over the background rate of endogenous lesions. The effe...

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Detalles Bibliográficos
Autores principales: Ames, B N, Shigenaga, M K, Gold, L S
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519422/
https://www.ncbi.nlm.nih.gov/pubmed/8013423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519422/
https://www.ncbi.nlm.nih.gov/pubmed/8013423

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