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Effect of methylene chloride inhalation on replicative DNA synthesis in the lungs of female B6C3F1 mice.
In the National Toxicology Program 2-year inhalation study of dichloromethane (DCM), there was a significant increase in pulmonary neoplasms in female B6C3F1 mice exposed to 2000 ppm (overall rates of 30/48 versus 5/50 in control). Replicative DNA synthesis was examined to evaluate the potential rol...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519431/ https://www.ncbi.nlm.nih.gov/pubmed/8013420 |