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Relationship between the time of sustained ethyl acrylate forestomach hyperplasia and carcinogenicity.

Chronic administration of ethyl acrylate (EA) by gavage at 100 or 200 mg/kg/day resulted in a significant dose-dependent increase in the incidence of forestomach (FS) squamous cell papillomas and carcinomas in both sexes of F344 rats and B6C3F1 mice. Subsequent work in this laboratory was designed t...

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Detalles Bibliográficos
Autores principales: Ghanayem, B I, Sanchez, I M, Maronpot, R R, Elwell, M R, Matthews, H B
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519444/
https://www.ncbi.nlm.nih.gov/pubmed/8013421