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Cellular origin of cancer: dedifferentiation or stem cell maturation arrest?
Given the fundamental principle that cancer must arise from a cell that has the potential to divide, two major nonexclusive hypotheses of the cellular origin of cancer are that malignancy arises a) from stem cells due to maturation arrest or b) from dedifferentiation of mature cells that retain the...
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| Formato: | Texto |
| Lenguaje: | English |
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1993
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519468/ https://www.ncbi.nlm.nih.gov/pubmed/7516873 |