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Biological bases for cancer dose-response extrapolation procedures.
The Moolgavkar-Knudson theory of carcinogenesis of 1981 incorporates the viable portions of earlier multistage theories and provides the basis for both the linearized multistage and biologically based dose-response extrapolation methodologies. This theory begins with the premise that cancer occurs b...
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Formato: | Texto |
Lenguaje: | English |
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1991
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519475/ https://www.ncbi.nlm.nih.gov/pubmed/2050075 |