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The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer.

Cytosolic glutathione S-transferases (GSTs) are a supergene family of dimeric enzymes capable of detoxifying a number of carcinogenic electrophiles. Of the numerous components of tobacco smoke, the polycyclic aromatic hydrocarbons appear to be the principal compounds that yield substrates for these...

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Detalles Bibliográficos
Autores principales: Ketterer, B, Harris, J M, Talaska, G, Meyer, D J, Pemble, S E, Taylor, J B, Lang, N P, Kadlubar, F F
Formato: Texto
Lenguaje:English
Publicado: 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519626/
https://www.ncbi.nlm.nih.gov/pubmed/1486868