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Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: histologic, biochemical, and cell proliferation endpoints.

The present study examines the dose-response relationship for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) promotion of histologic and biochemical parameters by using a two-stage model for hepatocarcinogenesis in female Sprague-Dawley rats initiated with a single intraperitoneal dose of 175 mg of diet...

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Detalles Bibliográficos
Autores principales: Maronpot, R R, Foley, J F, Takahashi, K, Goldsworthy, T, Clark, G, Tritscher, A, Portier, C, Lucier, G
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519881/
https://www.ncbi.nlm.nih.gov/pubmed/8143597