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Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: histologic, biochemical, and cell proliferation endpoints.
The present study examines the dose-response relationship for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) promotion of histologic and biochemical parameters by using a two-stage model for hepatocarcinogenesis in female Sprague-Dawley rats initiated with a single intraperitoneal dose of 175 mg of diet...
Autores principales: | Maronpot, R R, Foley, J F, Takahashi, K, Goldsworthy, T, Clark, G, Tritscher, A, Portier, C, Lucier, G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519881/ https://www.ncbi.nlm.nih.gov/pubmed/8143597 |
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