Noninvasive methods for measuring DNA alkylation in experimental animals and humans.

Alkylpurines are liberated from alkylated DNA by glycosylase repair enzymes and, in most cases, excreted in urine without further metabolism. This phenomenon forms the basis of noninvasive methods to measure DNA alkylation in vivo. In the case of methyl adducts, such as 7-methylguanine (7-MeGua), na...

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Detalles Bibliográficos
Autores principales: Shuker, D E, Prevost, V, Friesen, M D, Bartsch, H
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521165/
https://www.ncbi.nlm.nih.gov/pubmed/8143609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1521165/
https://www.ncbi.nlm.nih.gov/pubmed/8143609

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