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Using three-dimensional quantitative structure-activity relationships to examine estrogen receptor binding affinities of polychlorinated hydroxybiphenyls.

Certain phenyl-substituted hydrocarbons of environmental concern have the potential to disrupt the endocrine system of animals, apparently in association with their estrogenic properties. Competition with natural estrogens for the estrogen receptor is a possible mechanism by which such effects could...

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Detalles Bibliográficos
Autores principales: Waller, C L, Minor, D L, McKinney, J D
Formato: Texto
Lenguaje:English
Publicado: 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522195/
https://www.ncbi.nlm.nih.gov/pubmed/7588482