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Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System

Biological systems have evolved complex regulatory mechanisms, even in situations where much simpler designs seem to be sufficient for generating nominal functionality. Using module-based analysis coupled with rigorous mathematical comparisons, we propose that in analogy to control engineering archi...

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Detalles Bibliográficos
Autores principales: Kurata, Hiroyuki, El-Samad, Hana, Iwasaki, Rei, Ohtake, Hisao, Doyle, John C, Grigorova, Irina, Gross, Carol A, Khammash, Mustafa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523291/
https://www.ncbi.nlm.nih.gov/pubmed/16863396
http://dx.doi.org/10.1371/journal.pcbi.0020059