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The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C

Lassa virus glycoprotein is synthesised as a precursor (preGP-C) into the lumen of the endoplasmic reticulum. After cotranslational cleavage of the signal peptide, the immature GP-C is posttranslationally processed into the N-terminal subunit GP-1 and the C-terminal subunit GP-2 by the host cell sub...

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Detalles Bibliográficos
Autores principales: Eichler, Robert, Lenz, Oliver, Garten, Wolfgang, Strecker, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524727/
https://www.ncbi.nlm.nih.gov/pubmed/16737539
http://dx.doi.org/10.1186/1743-422X-3-41