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Akt1 sequentially phosphorylates p27(kip1 )within a conserved but non-canonical region
BACKGROUND: p27(kip1 )(p27) is a multifunctional protein implicated in regulation of cell cycling, signal transduction, and adhesion. Its activity is controlled in part by Phosphatylinositol-3-Kinase (PI3K)/Akt1 signaling, and disruption of this regulatory connection has been identified in human bre...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524731/ https://www.ncbi.nlm.nih.gov/pubmed/16780593 http://dx.doi.org/10.1186/1747-1028-1-11 |