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The Yin and Yang of centromeric cohesion of sister chromatids: mitotic kinases meet protein phosphatase 2A

Accurate chromosome segregation during meiosis and mitosis is essential for the maintenance of genomic stability. Defects in the regulation of chromosome segregation during division predispose cells to undergo mitotic catastrophe or neoplastic transformation. Cohesin, a molecular glue holding sister...

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Detalles Bibliográficos
Autores principales: Dai, Wei, Wang, Xiaoxing
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524732/
https://www.ncbi.nlm.nih.gov/pubmed/16759372
http://dx.doi.org/10.1186/1747-1028-1-9