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Characterization of the ribonuclease activity on the skin surface

The rapid degradation of ribonucleic acids (RNA) by ubiquitous ribonucleases limits the efficacy of new therapies based on RNA molecules. Therefore, our aim was to characterize the natural ribonuclease activities on the skin and in blood plasma i.e. at sites where many drugs in development are appli...

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Detalles Bibliográficos
Autores principales: Probst, Jochen, Brechtel, Sonja, Scheel, Birgit, Hoerr, Ingmar, Jung, Günther, Rammensee, Hans-Georg, Pascolo, Steve
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524753/
https://www.ncbi.nlm.nih.gov/pubmed/16732888
http://dx.doi.org/10.1186/1479-0556-4-4