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Characterization of the ribonuclease activity on the skin surface
The rapid degradation of ribonucleic acids (RNA) by ubiquitous ribonucleases limits the efficacy of new therapies based on RNA molecules. Therefore, our aim was to characterize the natural ribonuclease activities on the skin and in blood plasma i.e. at sites where many drugs in development are appli...
Autores principales: | Probst, Jochen, Brechtel, Sonja, Scheel, Birgit, Hoerr, Ingmar, Jung, Günther, Rammensee, Hans-Georg, Pascolo, Steve |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524753/ https://www.ncbi.nlm.nih.gov/pubmed/16732888 http://dx.doi.org/10.1186/1479-0556-4-4 |
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