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Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle

BACKGROUND: Evidence demonstrates that exogenously administered nitric oxide (NO) can induce insulin resistance in skeletal muscle. We have investigated the modulatory effects of two NO donors, S-nitroso-N-acetyl-D, L-penicillamine (SNAP) and S-nitrosoglutathione (GSNO) on the early events in insuli...

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Detalles Bibliográficos
Autores principales: Badal, Simone, Brown, Paul D, Ragoobirsingh, Dalip
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524779/
https://www.ncbi.nlm.nih.gov/pubmed/16729893
http://dx.doi.org/10.1186/1471-2091-7-17