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Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation – molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factor

BACKGROUND: The irregular formation of cytoskeletal fibers in spaceflown experimental cells has been observed, but the disorganization process of fibers is still poorly understood. It is well known that the activation of the small GTPase Rho leads to actin stress fibers assembly. This study was perf...

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Detalles Bibliográficos
Autores principales: Higashibata, Akira, Imamizo-Sato, Mari, Seki, Masaya, Yamazaki, Takashi, Ishioka, Noriaki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524780/
https://www.ncbi.nlm.nih.gov/pubmed/16803636
http://dx.doi.org/10.1186/1471-2091-7-19