Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

BACKGROUND: Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type TP53 5-FU-resistant cell lines, ContinB and ContinD, generated from the HCT116 colon cancer cell line, demonstrate moderate an...

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Detalles Bibliográficos
Autores principales: De Angelis, Paula M, Svendsrud, Debbie H, Kravik, Katherine L, Stokke, Trond
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524802/
https://www.ncbi.nlm.nih.gov/pubmed/16709241
http://dx.doi.org/10.1186/1476-4598-5-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524802/
https://www.ncbi.nlm.nih.gov/pubmed/16709241
http://dx.doi.org/10.1186/1476-4598-5-20

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