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Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

BACKGROUND: Treatment of cells with the anti-cancer drug 5-fluorouracil (5-FU) causes DNA damage, which in turn affects cell proliferation and survival. Two stable wild-type TP53 5-FU-resistant cell lines, ContinB and ContinD, generated from the HCT116 colon cancer cell line, demonstrate moderate an...

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Detalles Bibliográficos
Autores principales:	De Angelis, Paula M, Svendsrud, Debbie H, Kravik, Katherine L, Stokke, Trond
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524802/ https://www.ncbi.nlm.nih.gov/pubmed/16709241 http://dx.doi.org/10.1186/1476-4598-5-20

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