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The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers

BACKGROUND: The evolutionary conserved cyclin-dependent kinase phosphatase hCdc14A has been shown to play potential roles in the regulation of mitotic exit and in the centrosome duplication cycle. We have recently shown that hCdc14A also can interact with the tumor suppressor p53 both in vitro and i...

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Detalles Bibliográficos
Autores principales: Paulsen, Michelle T, Starks, Adrienne M, Derheimer, Frederick A, Hanasoge, Sheela, Li, Liwu, Dixon, Jack E, Ljungman, Mats
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524803/
https://www.ncbi.nlm.nih.gov/pubmed/16784539
http://dx.doi.org/10.1186/1476-4598-5-25