Cargando…

Lac repressor hinge flexibility and DNA looping: single molecule kinetics by tethered particle motion

The tethered particle motion (TPM) allows the direct detection of activity of a variety of biomolecules at the single molecule level. First pioneered for RNA polymerase, it has recently been applied also to other enzymes. In this work we employ TPM for a systematic investigation of the kinetics of D...

Descripción completa

Detalles Bibliográficos
Autores principales: Vanzi, Francesco, Broggio, Chiara, Sacconi, Leonardo, Pavone, Francesco Saverio
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524907/
https://www.ncbi.nlm.nih.gov/pubmed/16835309
http://dx.doi.org/10.1093/nar/gkl393