The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications

Epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptors. Its stimulation by endogenous ligands, EGF or transforming growth factor-alpha (TGF-α) results in activation of intracellular tyrosine kinase, therefore, cell cycle progression. High levels of EGFR expression are co...

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Detalles Bibliográficos
Autores principales: Zimmermann, Michel, Zouhair, Abderrahim, Azria, David, Ozsahin, Mahmut
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524965/
https://www.ncbi.nlm.nih.gov/pubmed/16722544
http://dx.doi.org/10.1186/1748-717X-1-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524965/
https://www.ncbi.nlm.nih.gov/pubmed/16722544
http://dx.doi.org/10.1186/1748-717X-1-11

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