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Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

BACKGROUND: Disrupting the balance of histone lysine methylation alters the expression of genes involved in tumorigenesis including proto-oncogenes and cell cycle regulators. Methylation of lysine residues is commonly catalyzed by a family of proteins that contain the SET domain. Here, we report the...

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Detalles Bibliográficos
Autores principales: Brown, Mark A, Sims, Robert J, Gottlieb, Paul D, Tucker, Philip W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524980/
https://www.ncbi.nlm.nih.gov/pubmed/16805913
http://dx.doi.org/10.1186/1476-4598-5-26