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Improving the specificity of high-throughput ortholog prediction

BACKGROUND: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative genomics and genome annotation. The gold standard phylogenetic analysis approach of comparing available organismal phyloge...

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Detalles Bibliográficos
Autores principales: Fulton, Debra L, Li, Yvonne Y, Laird, Matthew R, Horsman, Benjamin GS, Roche, Fiona M, Brinkman, Fiona SL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1524997/
https://www.ncbi.nlm.nih.gov/pubmed/16729895
http://dx.doi.org/10.1186/1471-2105-7-270