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Identification of specific calcitonin-like receptor residues important for calcitonin gene-related peptide high affinity binding

BACKGROUND: Calcitonin gene-related peptide (CGRP) is a vasoactive neuropeptide whose biological activity has potential therapeutic value for many vascular related diseases. CGRP is a 37 amino acid neuropeptide that signals through a G protein-coupled receptor belonging to the secretin receptor fami...

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Detalles Bibliográficos
Autores principales: Banerjee, Sugato, Evanson, Janel, Harris, Erik, Lowe, Stephen L, Thomasson, Kathryn A, Porter, James E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525162/
https://www.ncbi.nlm.nih.gov/pubmed/16776831
http://dx.doi.org/10.1186/1471-2210-6-9