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Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population
BACKGROUND: The protein tyrosine phosphatase-1B, a negative regulator for insulin and leptin signalling, potentially modulates glucose and energy homeostasis. PTP1B is encoded by the PTPN1 gene located on chromosome 20q13 showing linkage with type 2 diabetes (T2D) in several populations. PTPN1 gene...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525165/ https://www.ncbi.nlm.nih.gov/pubmed/16677372 http://dx.doi.org/10.1186/1471-2350-7-44 |