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Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy

BACKGROUND: In previous analyses we identified therapy-induced upregulation of the CDK inhibitor p21(CIP/WAF-1 )and consequently decreased tumor cell proliferation or loss of Bax as adverse factors for survival in rectal cancer treated with radiochemotherapy. Here, we address the individual role of...

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Detalles Bibliográficos
Autores principales: Sturm, Isrid, Rau, Beate, Schlag, Peter M, Wust, Peter, Hildebrandt, Bert, Riess, Hanno, Hauptmann, Steffen, Dörken, Bernd, Daniel, Peter T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525199/
https://www.ncbi.nlm.nih.gov/pubmed/16686938
http://dx.doi.org/10.1186/1471-2407-6-124