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Prostaglandin F2alpha- and FAS-activating antibody-induced regression of the corpus luteum involves caspase-8 and is defective in caspase-3 deficient mice

We recently demonstrated that caspase-3 is important for apoptosis during spontaneous involution of the corpus luteum (CL). These studies tested if prostaglandin F(2α )(PGF(2α)) or FAS regulated luteal regression, utilize a caspase-3 dependent pathway to execute luteal cell apoptosis, and if the two...

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Detalles Bibliográficos
Autores principales: Carambula, Silvia F, Pru, James K, Lynch, Maureen P, Matikainen, Tiina, Gonçalves, Paulo Bayard D, Flavell, Richard A, Tilly, Jonathan L, Rueda, Bo R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC152637/
https://www.ncbi.nlm.nih.gov/pubmed/12657159
http://dx.doi.org/10.1186/1477-7827-1-15