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Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro

Allergic rhinitis is an inflammatory disease characterized by nasal wall remodeling with intense infiltration of eosinophils and mast cells/basophils. Matrix metalloproteinases (MMPs), MMP-2 and MMP-9, are the major proteolytic enzymes that induce airway remodeling. These enzymes are also important...

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Detalles Bibliográficos
Autores principales: Shimizu, Toshiyuki, Kanai, Kenichi, Asano, Kazuhito, Hisamitsu, Tadashi, Suzaki, Harumi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526475/
https://www.ncbi.nlm.nih.gov/pubmed/16106101
http://dx.doi.org/10.1155/MI.2005.150