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Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro
Allergic rhinitis is an inflammatory disease characterized by nasal wall remodeling with intense infiltration of eosinophils and mast cells/basophils. Matrix metalloproteinases (MMPs), MMP-2 and MMP-9, are the major proteolytic enzymes that induce airway remodeling. These enzymes are also important...
Autores principales: | Shimizu, Toshiyuki, Kanai, Kenichi, Asano, Kazuhito, Hisamitsu, Tadashi, Suzaki, Harumi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526475/ https://www.ncbi.nlm.nih.gov/pubmed/16106101 http://dx.doi.org/10.1155/MI.2005.150 |
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