Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

BACKGROUND: Resistance of Plasmodium falciparum to atovaquone in vitro and in vivo has been associated to mutations in the parasite cytochrome b gene. METHODS: Cultures were sequentially subjected to increasing doses of atovaquone alone or in combination with cycloguanil and the cytochrome b gene wa...

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Detalles Bibliográficos
Autores principales: Schwöbel, Babett, Alifrangis, Michael, Salanti, Ali, Jelinek, Tomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC152655/
https://www.ncbi.nlm.nih.gov/pubmed/12665429
http://dx.doi.org/10.1186/1475-2875-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC152655/
https://www.ncbi.nlm.nih.gov/pubmed/12665429
http://dx.doi.org/10.1186/1475-2875-2-5

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