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Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

Arthritis is characterised by the proteolytic degradation of articular cartilage leading to a loss of joint function. Articular cartilage is composed of an extracellular matrix of proteoglycans and collagens. We have previously shown that serine proteinases are involved in the activation cascades le...

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Detalles Bibliográficos
Autores principales: Milner, Jennifer M, Kevorkian, Lara, Young, David A, Jones, Debra, Wait, Robin, Donell, Simon T, Barksby, Emma, Patterson, Angela M, Middleton, Jim, Cravatt, Benjamin F, Clark, Ian M, Rowan, Andrew D, Cawston, Timothy E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526559/
https://www.ncbi.nlm.nih.gov/pubmed/16507127
http://dx.doi.org/10.1186/ar1877