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Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1)

The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products involved in the pathogenesis of arthritis such as various cytokines and the CD40/CD40 ligand (CD40/CD40L) receptor-ligand dyad. The therapeutic ef...

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Detalles Bibliográficos
Autores principales: Hückel, Marion, Schurigt, Uta, Wagner, Andreas H, Stöckigt, Renate, Petrow, Peter K, Thoss, Klaus, Gajda, Mieczyslaw, Henzgen, Steffen, Hecker, Markus, Bräuer, Rolf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526583/
https://www.ncbi.nlm.nih.gov/pubmed/16507120
http://dx.doi.org/10.1186/ar1869