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Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1)
The transcription factor STAT-1 (signal transducer and activator of transcription-1) plays a pivotal role in the expression of inflammatory gene products involved in the pathogenesis of arthritis such as various cytokines and the CD40/CD40 ligand (CD40/CD40L) receptor-ligand dyad. The therapeutic ef...
Autores principales: | Hückel, Marion, Schurigt, Uta, Wagner, Andreas H, Stöckigt, Renate, Petrow, Peter K, Thoss, Klaus, Gajda, Mieczyslaw, Henzgen, Steffen, Hecker, Markus, Bräuer, Rolf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526583/ https://www.ncbi.nlm.nih.gov/pubmed/16507120 http://dx.doi.org/10.1186/ar1869 |
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