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The induction of CCN2 by TGFβ1 involves Ets-1

CCN2 is encoded by an immediate-early gene induced in mesenchymal cells during the formation of blood vessels, bone and connective tissue. It plays key roles in cell adhesion and migration, as well as matrix remodeling. CCN2 is overexpressed in fibrosis, arthritis and cancer; thus, an understanding...

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Detalles Bibliográficos
Autores principales: Van Beek, Jonathan P, Kennedy, Laura, Rockel, Jason S, Bernier, Suzanne M, Leask, Andrew
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526589/
https://www.ncbi.nlm.nih.gov/pubmed/16469114
http://dx.doi.org/10.1186/ar1890