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CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans

The chemokine CXCL12 (also known as stromal cell-derived factor, SDF-1) is constitutively expressed by stromal resident cells and is involved in the homeostatic and inflammatory traffic of leukocytes. Binding of CXCL12 to glycosaminoglycans on endothelial cells (ECs) is supposed to be relevant to th...

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Detalles Bibliográficos
Autores principales: Santiago, Begoña, Baleux, Françoise, Palao, Guillermo, Gutiérrez-Cañas, Irene, Ramírez, Juan C, Arenzana-Seisdedos, Fernando, Pablos, José L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526602/
https://www.ncbi.nlm.nih.gov/pubmed/16507142
http://dx.doi.org/10.1186/ar1900