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Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis

Recently, we proposed a classification of HLA-DRB1 alleles that reshapes the shared epitope hypothesis in rheumatoid arthritis (RA); according to this model, RA is associated with the RAA shared epitope sequence (72–74 positions) and the association is modulated by the amino acids at positions 70 an...

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Detalles Bibliográficos
Autores principales: Michou, Laëtitia, Croiseau, Pascal, Petit-Teixeira, Elisabeth, du Montcel, Sophie Tezenas, Lemaire, Isabelle, Pierlot, Céline, Osorio, José, Frigui, Wafa, Lasbleiz, Sandra, Quillet, Patrick, Bardin, Thomas, Prum, Bernard, Clerget-Darpoux, Françoise, Cornélis, François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526640/
https://www.ncbi.nlm.nih.gov/pubmed/16646982
http://dx.doi.org/10.1186/ar1949