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CD8(+) T-Cell Responses to Trypanosoma cruzi Are Highly Focused on Strain-Variant trans-Sialidase Epitopes

CD8(+) T cells are crucial for control of a number of medically important protozoan parasites, including Trypanosoma cruzi, the agent of human Chagas disease. Yet, in contrast to the wealth of information from viral and bacterial infections, little is known about the antigen specificity or the gener...

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Detalles Bibliográficos
Autores principales: Martin, Diana L, Weatherly, D. Brent, Laucella, Susana A, Cabinian, Melissa A, Crim, Matthew T, Sullivan, Susan, Heiges, Mark, Craven, Sarah H, Rosenberg, Charles S, Collins, Matthew H, Sette, Alessandro, Postan, Miriam, Tarleton, Rick L
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526708/
https://www.ncbi.nlm.nih.gov/pubmed/16879036
http://dx.doi.org/10.1371/journal.ppat.0020077