Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia

BACKGROUND: Stroke is one of the leading causes of death worldwide and a major cause of morbidity and mortality in the United States of America. Brain ischemia-reperfusion (IR) triggers a complex series of biochemical events including inflammation. Leukotrienes derived from 5-lipoxygenase (5-LOX) ca...

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Detalles Bibliográficos
Autores principales: Jatana, Manu, Giri, Shailendra, Ansari, Mubeen A, Elango, Chinnasamy, Singh, Avtar K, Singh, Inderjit, Khan, Mushfiquddin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526713/
https://www.ncbi.nlm.nih.gov/pubmed/16689995
http://dx.doi.org/10.1186/1742-2094-3-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526713/
https://www.ncbi.nlm.nih.gov/pubmed/16689995
http://dx.doi.org/10.1186/1742-2094-3-12

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