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Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia

BACKGROUND: Stroke is one of the leading causes of death worldwide and a major cause of morbidity and mortality in the United States of America. Brain ischemia-reperfusion (IR) triggers a complex series of biochemical events including inflammation. Leukotrienes derived from 5-lipoxygenase (5-LOX) ca...

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Detalles Bibliográficos
Autores principales:	Jatana, Manu, Giri, Shailendra, Ansari, Mubeen A, Elango, Chinnasamy, Singh, Avtar K, Singh, Inderjit, Khan, Mushfiquddin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526713/ https://www.ncbi.nlm.nih.gov/pubmed/16689995 http://dx.doi.org/10.1186/1742-2094-3-12

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