Evaluation of antibodies against human HSP60 in patients with MPO-ANCA associated glomerulonephritis: a cohort study

BACKGROUND: Human Heat Shock Protein 60 (hHSP60) has been implicated in autoimmunity through molecular mimicry, based on the high degree of homology with HSP65 of micro-organisms leading to autoimmune recognition of the human protein. Additionally, sequence homology between hHSP60 and myeloperoxidas...

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Autores principales: Slot, Marjan C, Theunissen, Ruud, van Paassen, Pieter, Damoiseaux, Jan GMC, Cohen Tervaert, Jan Willem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526731/
https://www.ncbi.nlm.nih.gov/pubmed/16677376
http://dx.doi.org/10.1186/1740-2557-3-4