Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens

BACKGROUND: Glutamate, a major excitatory amino acid neurotransmitter, causes apoptotic neuronal cell death at high concentrations. Our previous studies have shown that depending on the neuronal cell type, glutamate-induced apoptotic cell death was associated with regulation of genes such as Bcl-2,...

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Detalles Bibliográficos
Autores principales: Zhang, YueMei, Bhavnani, Bhagu R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526740/
https://www.ncbi.nlm.nih.gov/pubmed/16776830
http://dx.doi.org/10.1186/1471-2202-7-49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526740/
https://www.ncbi.nlm.nih.gov/pubmed/16776830
http://dx.doi.org/10.1186/1471-2202-7-49

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