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Interactions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1

BACKGROUND: Nef is an accessory protein of primate lentiviruses, HIV-1, HIV-2 and SIV. Besides removing CD4 and MHC class I from the surface and activating cellular signaling cascades, Nef also binds GagPol during late stages of the viral replicative cycle. In this report, we investigated further th...

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Detalles Bibliográficos
Autores principales: Costa, Luciana J, Chen, Nan, Lopes, Adriana, Aguiar, Renato S, Tanuri, Amilcar, Plemenitas, Ana, Peterlin, B Matija
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526754/
https://www.ncbi.nlm.nih.gov/pubmed/16764724
http://dx.doi.org/10.1186/1742-4690-3-33