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Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype.

Differential CYP1A1 inducibility, reflecting variations in aromatic hydrocarbon receptor (AHR) affinity among inbred mouse strains, is an important determinant of environmental toxicity. We took advantage of the Ahr polymorphism in C57BL/6 and DBA/2 mice to develop an oligonucleotide-hybridization s...

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Detalles Bibliográficos
Autores principales: Maier, A, Micka, J, Miller, K, Denko, T, Chang, C Y, Nebert, D W, Alvaro Puga
Formato: Texto
Lenguaje:English
Publicado: 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533118/
https://www.ncbi.nlm.nih.gov/pubmed/9637800