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N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients

BACKGROUND: N-acetyltransferase 2 (NAT2) metabolizes arylamines and hydrazines moeities found in many therapeutic drugs, chemicals and carcinogens. The gene encoding NAT2 is polymorphic, thus resulting in rapid or slow acetylator phenotypes. The acetylator status may, therefore, predispose drug-indu...

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Detalles Bibliográficos
Autores principales: Borlak, Juergen, Reamon-Buettner, Stella Marie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533812/
https://www.ncbi.nlm.nih.gov/pubmed/16827944
http://dx.doi.org/10.1186/1471-2350-7-58