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Mutations in PIK3CA are infrequent in neuroblastoma

BACKGROUND: Neuroblastoma is a frequently lethal pediatric cancer in which MYCN genomic amplification is highly correlated with aggressive disease. Deregulated MYC genes require co-operative lesions to foster tumourigenesis and both direct and indirect evidence support activated Ras signaling for th...

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Detalles Bibliográficos
Autores principales: Dam, Vincent, Morgan, Brian T, Mazanek, Pavel, Hogarty, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1533846/
https://www.ncbi.nlm.nih.gov/pubmed/16822308
http://dx.doi.org/10.1186/1471-2407-6-177